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    MAIN is an interactively driven computer program dealing with computational parts of macromolecular crystallography in progressively automated manner: 1) visualization and interactive modeling of molecular structures; 2) density modifications (solvent flattening and flipping, envelopes manipulation, averaging); 3) crystallographic refinement (real space and reciprocal space target); and 4) structure analysis and validation.


    v. 2006


    OSX, Linux, Irix

Documentation, Other Resources


    Turk, D. (1992) Weiterentwicklung eines Programms fuer Molekuelgraphik und Elektrondichte-Manipulation und seine Anwendung auf verschiedene Protein-Strukturaufklaerungen. Ph.D. Thesis, Technische Universitaet, Muenchen.

    D.Turk: "MAIN 96: An interactive software for density modifications, model building, structure refinement and analysis." Proceedings from the 1996 meeting of the International Union of Crystallography Macromolecular Macromolecular Computing School, eds P.E. Bourne & K. Watenpaugh This 'MAIN 96' paper is included in the proceedings of the IUCr 96 Computational School and will obviously NOT be published.

    Turk, D. (2001) Towards Automatic Macromolecular Crystal Structure Determination. Methods in Macromolecular Crystallography. (Eds Turk. D, Johnson, L) NATO Science Series I, vol 325, ISBN: 1 58603 080 9 (IOS Press), 148-155.

Last modified: 12/27/06